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Circulation 143 (21), e984e1010

Stevens et al

This side effect isnt quite as easy to pinpoint

The low representation of tirzepatide likely reflects its recent introduction in 2023 [11], whereas the high frequency of exenatide reports can be attributed to its earlier approval in 2005 [29]

In Eli Lillys clinical pharmacology data submitted to the FDA, a single 5 mg dose of tirzepatide reduced the maximum concentration of a birth control pill by roughly half and reduced overall exposure by about 20%